Virtual team work became a pivotal part of the knowledge workers and the companies life of today, reflecting the opportunities created by globalization, technological advancements and changes in the way we work. Unfortunately, while virtual teaming is extremely useful, it also presents a number of highly specialized challenges, pushing employees into the importance of heaving unique skills and capabilities. The master thesis is aimed at taking a deeper look at the challenges of virtual team work, and how can an organisation respond and meet the given hardships by putting an emphasis on the preparation and training of new employees. Following a brief introduction on the history and development of virtual teamwork, the literature review highlights the challenges faced by employees working in virtual teams. These include, leadership, communication, culture, technology, trust and conflict management. The research question, “How should new employees be prepared for the challenges of virtual team work?” is then investigated in real-life context based on the findings of the literature. Ten employees from Intel, Linz were interviewed through one month period giving an actual snapshot of the issues and possible solutions. From the above listed challenges, employees found communication, culture and technology as important issues. They expressed that these are the challenges new employees should get training about in the form of instructor-led classroom training with supporting material in the form of online repository. Further investigation is suggested, as the research sample is reflecting the view of one company in the semi-conductor industry, which is highly specialized in terms of employee blend. Additionally, through the interviews it became evident that the corporate culture has an effect on virtual teamwork which could be further explored and understood.